Whole-genome methylation analysis reveals novel epigenetic perturbations of congenital scoliosis

Congenital scoliosis (CS) is a congenital disease caused by malformations of vertebrae. Recent studies demonstrated that DNA modification could contribute to the pathogenesis of disease. This study aims to identify epigenetic perturbations that may contribute to the pathogenesis of CS. Four CS patie...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Liu, Gang, Zhao, Hengqiang, Yan, Zihui, Zhao, Sen, Niu, Yuchen, Li, Xiaoxin, Wang, Shengru, Yang, Yang, Liu, Sen, Zhang, Terry Jianguo, Wu, Zhihong, Wu, Nan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2021
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907230/
https://ncbi.nlm.nih.gov/pubmed/33717649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.02.002
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