Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures

PURPOSE: Fibroblast growth factor receptors (FGFR) and pathways are important players in breast cancer (BC) development. They are commonly altered, and BCs exhibiting FGFR gene amplification are currently being studied for drug development. Here, we aimed to compare the effects of three FGFR inhibit...

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Detalhes bibliográficos
Publicado no:Cell Oncol (Dordr)
Main Authors: Kähkönen, T. E., Toriseva, M., Petruk, N., Virta, A.-R., Maher, A., Eigéliené, N., Kaivola, J., Boström, P., Koskivuo, I., Nees, M., Tuomela, J. M., Ivaska, K. K., Härkönen, P. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2020
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907049/
https://ncbi.nlm.nih.gov/pubmed/33119860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-020-00562-0
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