A carregar...
Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model
Achondroplasia (ACH) is the most frequent form of dwarfism and is caused by gain-of-function mutations in the fibroblast growth factor receptor 3–encoding (FGFR3-encoding) gene. Although potential therapeutic strategies for ACH, which aim to reduce excessive FGFR3 activation, have emerged over many...
Na minha lista:
Publicado no: | J Clin Invest |
---|---|
Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2016
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855917/ https://ncbi.nlm.nih.gov/pubmed/27064282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83926 |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|