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Oxaliplatin induces the PARP1-mediated parthanatos in oral squamous cell carcinoma by increasing production of ROS

Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors worldwide, and its prognosis is still not optimistic. Oxaliplatin is a type of platinum chemotherapeutic agent, but its treatment effects on OSCC and molecular mechanisms have not been fully elucidated. Parthanatos, a uni...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Li, Dongfang, Kou, Yuying, Gao, Yuan, Liu, Shanshan, Yang, Panpan, Hasegawa, Tomoka, Su, Rongjian, Guo, Jie, Li, Minqi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906208/
https://ncbi.nlm.nih.gov/pubmed/33495407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202386
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