Oxaliplatin induces the PARP1-mediated parthanatos in oral squamous cell carcinoma by increasing production of ROS

Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors worldwide, and its prognosis is still not optimistic. Oxaliplatin is a type of platinum chemotherapeutic agent, but its treatment effects on OSCC and molecular mechanisms have not been fully elucidated. Parthanatos, a uni...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Li, Dongfang, Kou, Yuying, Gao, Yuan, Liu, Shanshan, Yang, Panpan, Hasegawa, Tomoka, Su, Rongjian, Guo, Jie, Li, Minqi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906208/
https://ncbi.nlm.nih.gov/pubmed/33495407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202386
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