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Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway

Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms. MG-63 cells were exposed to DADs (0, 20, 40, 60, 80,...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yue, Ziqi, Guan, Xin, Chao, Rui, Huang, Cancan, Li, Dongfang, Yang, Panpan, Liu, Shanshan, Hasegawa, Tomoka, Guo, Jie, Li, Minqi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681087/
https://ncbi.nlm.nih.gov/pubmed/31340526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24142665
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