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The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage

Bupivacaine has been widely used in clinical Anesthesia, but its neurotoxicity has been frequently reported, implicating cellular oxidative DNA damage as the major underlying mechanism. However, the mechanism underlying bupivacaine-induced oxidative DNA damage is unknown. We, thus, exposed SH-SY5Y c...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Main Authors: Zhao, Wei, Liu, Zhongjie, Luo, Jiaming, Ma, Changqing, Lai, Luying, Xia, Zhengyuan, Xu, Shiyuan
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906168/
https://ncbi.nlm.nih.gov/pubmed/33495403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202390
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