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The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage

Bupivacaine has been widely used in clinical Anesthesia, but its neurotoxicity has been frequently reported, implicating cellular oxidative DNA damage as the major underlying mechanism. However, the mechanism underlying bupivacaine-induced oxidative DNA damage is unknown. We, thus, exposed SH-SY5Y c...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Zhao, Wei, Liu, Zhongjie, Luo, Jiaming, Ma, Changqing, Lai, Luying, Xia, Zhengyuan, Xu, Shiyuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906168/
https://ncbi.nlm.nih.gov/pubmed/33495403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202390
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