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In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine
PURPOSE: To investigate the metabolic pathways of triapine in primary cultures of human hepatocytes and human hepatic subcellular fractions; to investigate interactions of triapine with tenofovir and emtricitabine; and to evaluate triapine as a perpetrator of drug interactions. The results will bett...
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| Udgivet i: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7906094/ https://ncbi.nlm.nih.gov/pubmed/32989483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04154-5 |
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