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Bicyclic Chalcones as Mitotic Inhibitors for Overcoming Androgen Receptor-Independent and Multidrug-Resistant Prostate Cancer
[Image: see text] To improve the biological effects of the lead compound 5′-chloro-2,2′-dihydroxychalcone (Cl-DHC), bicyclic aromatic chalcones were designed, synthesized, and evaluated against androgen-independent prostate cancer (PCa) DU145 and PC-3 cell proliferation. Newly synthesized bi-naphthy...
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| Publicado en: | ACS Omega |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2021
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905931/ https://ncbi.nlm.nih.gov/pubmed/33644592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05822 |
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