DNMT1 and DNMT3B regulate tumorigenicity of human prostate cancer cells by controlling RAD9 expression through targeted methylation

Prostate cancer is the second most common type of cancer and the second leading cause of cancer death in American men. RAD9 stabilizes the genome, but prostate cancer cells and tumors often have high quantities of the protein. Reduction of RAD9 level within prostate cancer cells decreases tumorigeni...

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Vydáno v:Carcinogenesis
Hlavní autoři: Zhu, Aiping, Hopkins, Kevin M, Friedman, Richard A, Bernstock, Joshua D, Broustas, Constantinos G, Lieberman, Howard B
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Carcinogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905840/
https://ncbi.nlm.nih.gov/pubmed/32780107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa088
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