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RAD9A promotes metastatic phenotypes through transcriptional regulation of anterior gradient 2 (AGR2)
RAD9A plays an important role in prostate tumorigenesis and metastasis-related phenotypes. The protein classically functions as part of the RAD9A-HUS1-RAD1 complex but can also act independently. RAD9A can selectively transactivate multiple genes, including CDKN1A and NEIL1 by binding p53-consensus...
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| Publicado no: | Carcinogenesis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6412126/ https://ncbi.nlm.nih.gov/pubmed/30295739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy131 |
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