RAD9A promotes metastatic phenotypes through transcriptional regulation of anterior gradient 2 (AGR2)

RAD9A plays an important role in prostate tumorigenesis and metastasis-related phenotypes. The protein classically functions as part of the RAD9A-HUS1-RAD1 complex but can also act independently. RAD9A can selectively transactivate multiple genes, including CDKN1A and NEIL1 by binding p53-consensus...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Carcinogenesis
Egile Nagusiak: Broustas, Constantinos G, Hopkins, Kevin M, Panigrahi, Sunil K, Wang, Li, Virk, Renu K, Lieberman, Howard B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Carcinogenesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412126/
https://ncbi.nlm.nih.gov/pubmed/30295739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy131
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