Rad9 Protein Contributes to Prostate Tumor Progression by Promoting Cell Migration and Anoikis Resistance

Rad9 as part of the Rad9-Hus1-Rad1 complex is known to participate in cell cycle checkpoint activation and DNA repair. However, Rad9 can act as a sequence-specific transcription factor, modulating expression of a number of genes. Importantly, Rad9 is up-regulated in prostate cancer cell lines and cl...

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Bibliographic Details
Main Authors: Broustas, Constantinos G., Zhu, Aiping, Lieberman, Howard B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510830/
https://ncbi.nlm.nih.gov/pubmed/23066031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.402784
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