Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms

Stable atherosclerotic plaques are characterized by a thick extracellular matrix (ECM)-rich fibrous cap populated by protective ACTA2(+) myofibroblast (MF)-like cells, assumed to be almost exclusively derived from smooth muscle cells (SMC). Herein, we show that in murine and human lesions, 20 to 40%...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Metab
Main Authors: Newman, Alexandra AC, Serbulea, Vlad, Baylis, Richard A, Shankman, Laura S, Bradley, Xenia, Alencar, Gabriel F, Owsiany, Katherine, Deaton, Rebecca A, Karnewar, Santosh, Shamsuzzaman, Sohel, Salamon, Anita, Reddy, Mahima S, Guo, Liang, Finn, Aloke, Virmani, Renu, Cherepanova, Olga A, Owens, Gary K
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905710/
https://ncbi.nlm.nih.gov/pubmed/33619382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-00338-8
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker