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Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice
Lipophilic statins which are blood brain barrier (BBB) permeable are speculated to affect the cholesterol synthesis and neural functions in the central nervous system. However, whether these statins can affect cholesterol levels and synaptic plasticity in hippocampus and the in vivo consequence rema...
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| Publicado no: | Mol Brain |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905661/ https://ncbi.nlm.nih.gov/pubmed/33627175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00758-x |
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