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Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice

Lipophilic statins which are blood brain barrier (BBB) permeable are speculated to affect the cholesterol synthesis and neural functions in the central nervous system. However, whether these statins can affect cholesterol levels and synaptic plasticity in hippocampus and the in vivo consequence rema...

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Bibliografski detalji
Izdano u:Mol Brain
Glavni autori: Guo, Yujun, Zou, Guichang, Qi, Keke, Jin, Jin, Yao, Lei, Pan, Yang, Xiong, Wei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905661/
https://ncbi.nlm.nih.gov/pubmed/33627175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00758-x
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