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PASTA: PARP activity screening and inhibitor testing assay

Small-molecule inhibitors have been instrumental in uncovering the biological importance of poly-ADP-ribose polymerases (PARPs), a family of enzymes involved in wide-ranging aspects of cell biology. However, few PARP inhibitors are tested against the entire family of PARPs. This makes it impossible...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Kirby, Ilsa T., Sanderson, Daniel J., Cohen, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905464/
https://ncbi.nlm.nih.gov/pubmed/33665624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100344
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