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PASTA: PARP activity screening and inhibitor testing assay
Small-molecule inhibitors have been instrumental in uncovering the biological importance of poly-ADP-ribose polymerases (PARPs), a family of enzymes involved in wide-ranging aspects of cell biology. However, few PARP inhibitors are tested against the entire family of PARPs. This makes it impossible...
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| Veröffentlicht in: | STAR Protoc |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905464/ https://ncbi.nlm.nih.gov/pubmed/33665624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100344 |
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