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Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages

Nitric oxide (NO) reacts with superoxide to produce peroxynitrite, a potent oxidant and reportedly exerts cytotoxic action. Herein we validated the hypothesis that interaction of NO with superoxide exerts protection against superoxide toxicity using macrophages from mice with a knockout (KO) of indu...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Kobayashi, Sho, Homma, Takujiro, Fujii, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905073/
https://ncbi.nlm.nih.gov/pubmed/33665378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.100942
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