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Verteporfin inhibits the persistent fibrotic phenotype of lesional scleroderma dermal fibroblasts
Fibrosis is perpetuated by an autocrine, pro-adhesive signaling loop maintained by the synthetic and contractile abilities of myofibroblasts and the stiff, highly-crosslinked extracellular matrix. Transcriptional complexes that are exquisitely responsive to mechanotransduction include the co-activat...
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| Publicado no: | J Cell Commun Signal |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905010/ https://ncbi.nlm.nih.gov/pubmed/33398723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-020-00596-x |
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