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Prediction of drug–target binding affinity using similarity-based convolutional neural network

Identifying novel drug–target interactions (DTIs) plays an important role in drug discovery. Most of the computational methods developed for predicting DTIs use binary classification, whose goal is to determine whether or not a drug–target (DT) pair interacts. However, it is more meaningful but also...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Shim, Jooyong, Hong, Zhen-Yu, Sohn, Insuk, Hwang, Changha
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904939/
https://ncbi.nlm.nih.gov/pubmed/33627791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83679-y
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