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SE-OnionNet: A Convolution Neural Network for Protein–Ligand Binding Affinity Prediction

Deep learning methods, which can predict the binding affinity of a drug–target protein interaction, reduce the time and cost of drug discovery. In this study, we propose a novel deep convolutional neural network called SE-OnionNet, with two squeeze-and-excitation (SE) modules, to computationally pre...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wang, Shudong, Liu, Dayan, Ding, Mao, Du, Zhenzhen, Zhong, Yue, Song, Tao, Zhu, Jinfu, Zhao, Renteng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962986/
https://ncbi.nlm.nih.gov/pubmed/33737946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.607824
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