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Prediction of drug–target binding affinity using similarity-based convolutional neural network

Identifying novel drug–target interactions (DTIs) plays an important role in drug discovery. Most of the computational methods developed for predicting DTIs use binary classification, whose goal is to determine whether or not a drug–target (DT) pair interacts. However, it is more meaningful but also...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Shim, Jooyong, Hong, Zhen-Yu, Sohn, Insuk, Hwang, Changha
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904939/
https://ncbi.nlm.nih.gov/pubmed/33627791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83679-y
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