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Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease

Accumulating evidence has suggested that the molecular transcriptional mechanism contributes to Alzheimer’s disease (AD) and its endophenotypes of cognitive decline and neuropathological traits, β-amyloid (Aβ) and phosphorylated tangles (TAU). However, it is unknown what is the impact of the AD risk...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: De Jager, Céline H., White, Charles C., Bennett, David A., Ma, Yiyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904919/
https://ncbi.nlm.nih.gov/pubmed/33627625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01253-6
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