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Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease

Accumulating evidence has suggested that the molecular transcriptional mechanism contributes to Alzheimer’s disease (AD) and its endophenotypes of cognitive decline and neuropathological traits, β-amyloid (Aβ) and phosphorylated tangles (TAU). However, it is unknown what is the impact of the AD risk...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: De Jager, Céline H., White, Charles C., Bennett, David A., Ma, Yiyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904919/
https://ncbi.nlm.nih.gov/pubmed/33627625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01253-6
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