Genome-Wide DNA Methylation Differences Between Late-Onset Alzheimer’s Disease and Cognitively Normal Controls in Human Frontal Cortex

Evidence supports a role for epigenetic mechanisms in the pathogenesis of late-onset Alzheimer’s disease (LOAD), but little has been done on a genome-wide scale to identify potential sites involved in disease. This study investigates human postmortem frontal cortex genome-wide DNA methylation profil...

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Autors principals: Bakulski, Kelly M., Dolinoy, Dana C., Sartor, Maureen A., Paulson, Henry L., Konen, John R., Lieberman, Andrew P., Albin, Roger L., Hu, Howard, Rozek, Laura S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652332/
https://ncbi.nlm.nih.gov/pubmed/22451312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-111223
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