Spatially mapped single-cell chromatin accessibility

High-throughput single-cell epigenomic assays can resolve cell type heterogeneity in complex tissues, however, spatial orientation is lost. Here, we present single-cell combinatorial indexing on Microbiopsies Assigned to Positions for the Assay for Transposase Accessible Chromatin, or sciMAP-ATAC, a...

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Udgivet i:Nat Commun
Main Authors: Thornton, Casey A., Mulqueen, Ryan M., Torkenczy, Kristof A., Nishida, Andrew, Lowenstein, Eve G., Fields, Andrew J., Steemers, Frank J., Zhang, Wenri, McConnell, Heather L., Woltjer, Randy L., Mishra, Anusha, Wright, Kevin M., Adey, Andrew C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904839/
https://ncbi.nlm.nih.gov/pubmed/33627658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21515-7
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