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Sequencing thousands of single-cell genomes with combinatorial indexing

Single-cell genome sequencing has proven valuable for the detection of somatic variation, particularly in the context of tumor evolution. Current technologies suffer from high library construction costs which restrict the number of cells that can be assessed and thus impose limitations on the abilit...

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Udgivet i:Nat Methods
Main Authors: Vitak, Sarah A., Torkenczy, Kristof A., Rosenkrantz, Jimi L., Fields, Andrew J., Christiansen, Lena, Wong, Melissa H., Carbone, Lucia, Steemers, Frank J., Adey, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908213/
https://ncbi.nlm.nih.gov/pubmed/28135258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4154
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