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Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion
TP53 (p53) is a pivotal player in tumor suppression with fifty percent of all invasive tumors displaying mutations in the TP53 gene. In the present study, we characterized colon cancer cells (HCT116 p53 (−/−)) with TP53 deletion, a sub-line derived from HCT116-p53 (+/+) cells. RNA sequencing and net...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904745/ https://ncbi.nlm.nih.gov/pubmed/33515271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-02979-4 |
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