טוען...

Pre-treatment with high molecular weight free PEG effectively suppresses anti-PEG antibody induction by PEG-liposomes in mice

Immune responses against polyethylene glycol (PEG) can lead to the rapid clearance of PEGylated drugs and are associated with increased risk of serious adverse events such as infusion reactions and anaphylaxis. Although select PEGylated therapeutics can induce anti-PEG antibodies (APA), there is cur...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Control Release
Main Authors: McSweeney, Morgan D., Shen, Limei, DeWalle, Alexander C., Joiner, Jordan B., Ciociola, Elizabeth C., Raghuwanshi, Dharmendra, Macauley, Matthew S., Lai, Samuel K.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904660/
https://ncbi.nlm.nih.gov/pubmed/33038448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.10.011
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