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TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria and sequentially triggers two signaling cascades: the first one involving TIRAP and MyD88 ad...
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| 發表在: | Cell Mol Life Sci |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer International Publishing
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904555/ https://ncbi.nlm.nih.gov/pubmed/33057840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03656-y |
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