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CD14 Mediates Binding of High Doses of LPS but Is Dispensable for TNF-α Production
Activation of macrophages with lipopolysaccharide (LPS) involves a sequential engagement of serum LPS-binding protein (LBP), plasma membrane CD14, and TLR4/MD-2 signaling complex. We analyzed participation of CD14 in TNF-α production stimulated with 1–1000 ng/mL of smooth or rough LPS (sLPS or rLPS)...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Hindawi Publishing Corporation
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892557/ https://ncbi.nlm.nih.gov/pubmed/24489448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/824919 |
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