CD14 Mediates Binding of High Doses of LPS but Is Dispensable for TNF-α Production

Activation of macrophages with lipopolysaccharide (LPS) involves a sequential engagement of serum LPS-binding protein (LBP), plasma membrane CD14, and TLR4/MD-2 signaling complex. We analyzed participation of CD14 in TNF-α production stimulated with 1–1000 ng/mL of smooth or rough LPS (sLPS or rLPS)...

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Bibliografiska uppgifter
Huvudupphovsmän: Borzęcka, Kinga, Płóciennikowska, Agnieszka, Björkelund, Hanna, Sobota, Andrzej, Kwiatkowska, Katarzyna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892557/
https://ncbi.nlm.nih.gov/pubmed/24489448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/824919
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