Association of Lyn kinase with membrane rafts determines its negative influence on LPS-induced signaling

Lipopolysaccharide (LPS) is the component of Gram-negative bacteria that activates Toll-like receptor 4 (TLR4) to trigger proinflammatory responses. We examined the involvement of Lyn tyrosine kinase in TLR4 signaling of macrophages, distinguishing its catalytic activity and intermolecular interacti...

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Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Borzęcka-Solarz, Kinga, Dembińska, Justyna, Hromada-Judycka, Aneta, Traczyk, Gabriela, Ciesielska, Anna, Ziemlińska, Ewelina, Świątkowska, Anna, Kwiatkowska, Katarzyna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2017
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391190/
https://ncbi.nlm.nih.gov/pubmed/28228554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0632
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