Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters

SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was derived from an IgM memory B cell of a COVID-19 patient, has high affinity for the Spike protein receptor binding dom...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep Med
Egile Nagusiak: Piepenbrink, Michael S., Park, Jun-Gyu, Oladunni, Fatai S., Deshpande, Ashlesha, Basu, Madhubanti, Sarkar, Sanghita, Loos, Andreas, Woo, Jennifer, Lovalenti, Phillip, Sloan, Derek, Ye, Chengjin, Chiem, Kevin, Bates, Christopher W., Burch, Reuben E., Erdmann, Nathaniel B., Goepfert, Paul A., Truong, Vu L., Walter, Mark R., Martinez-Sobrido, Luis, Kobie, James J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904445/
https://ncbi.nlm.nih.gov/pubmed/33649747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100218
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