Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters

SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was derived from an IgM memory B cell of a COVID-19 patient, has high affinity for the Spike protein receptor binding dom...

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Publicado no:Cell Rep Med
Main Authors: Piepenbrink, Michael S., Park, Jun-Gyu, Oladunni, Fatai S., Deshpande, Ashlesha, Basu, Madhubanti, Sarkar, Sanghita, Loos, Andreas, Woo, Jennifer, Lovalenti, Phillip, Sloan, Derek, Ye, Chengjin, Chiem, Kevin, Bates, Christopher W., Burch, Reuben E., Erdmann, Nathaniel B., Goepfert, Paul A., Truong, Vu L., Walter, Mark R., Martinez-Sobrido, Luis, Kobie, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904445/
https://ncbi.nlm.nih.gov/pubmed/33649747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100218
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