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IL-33 enhances the kinetics and quality of the antibody response to a DNA and protein-based HIV-1 Env vaccine

Induction of a sustained and broad antibody (Ab) response is a major goal in developing a protective HIV-1 vaccine. DNA priming alone shows reduced levels of immunogenicity; however, when combined with protein boosting is an attractive vaccination strategy for induction of humoral responses. Using t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Sarkar, Sanghita, Piepenbrink, Michael S., Basu, Madhubanti, Thakar, Juilee, Keefer, Michael C., Hessell, Ann J., Haigwood, Nancy L., Kobie, James J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506229/
https://ncbi.nlm.nih.gov/pubmed/30926296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.03.044
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