Functional and Molecular Characteristics of Novel and Conserved Cross-Clade HIV Envelope Specific Human Monoclonal Antibodies

To define features of the B cell response to HIV that may be translated to vaccine development, we have isolated a panel of monoclonal antibodies (MAbs) from HIV-infected patients. These MAbs are all highly reactive to HIV envelope (Env) from multiple clades, and include gp120 and gp41 specificities...

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Publicat a:Monoclon Antib Immunodiagn Immunother
Autors principals: Kobie, James J., Zheng, Bo, Piepenbrink, Michael S., Hessell, Ann J., Haigwood, Nancy L., Keefer, Michael C., Sanz, Ignacio
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410305/
https://ncbi.nlm.nih.gov/pubmed/25897603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2014.0064
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