Hypoxia-Induced Autophagy Enhances Cisplatin Resistance in Human Bladder Cancer Cells by Targeting Hypoxia-Inducible Factor-1α

PURPOSE: To investigate the effect of hypoxia on chemoresistance and the underlying mechanism in bladder cancer cells. METHODS: BIU-87 bladder cancer cell line was treated with cisplatin under hypoxic and normoxic conditions and tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromi...

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Vydáno v:J Immunol Res
Hlavní autoři: Mao, Xiawa, Nanzhang, Xiao, Jiaquao, Wu, Huifeng, Ding, Kefeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904373/
https://ncbi.nlm.nih.gov/pubmed/33681390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8887437
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