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Hypoxia-Induced Autophagy Enhances Cisplatin Resistance in Human Bladder Cancer Cells by Targeting Hypoxia-Inducible Factor-1α

PURPOSE: To investigate the effect of hypoxia on chemoresistance and the underlying mechanism in bladder cancer cells. METHODS: BIU-87 bladder cancer cell line was treated with cisplatin under hypoxic and normoxic conditions and tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromi...

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Bibliographic Details
Published in:J Immunol Res
Main Authors: Mao, Xiawa, Nanzhang, Xiao, Jiaquao, Wu, Huifeng, Ding, Kefeng
Format: Artigo
Language:Inglês
Published: Hindawi 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904373/
https://ncbi.nlm.nih.gov/pubmed/33681390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8887437
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