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Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells

Hypoxia which commonly exists in solid tumors, leads to cancer cells chemoresistance via provoking adaptive responses including autophagy. Therefore, we sought to evaluate the role of autophagy and hypoxia as well as the underlying mechanism in the cisplatin resistance of lung cancer cells. Our stud...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wu, Hui-Mei, Jiang, Zi-Feng, Ding, Pei-Shan, Shao, Li-Jie, Liu, Rong-Yu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511870/
https://ncbi.nlm.nih.gov/pubmed/26201611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12291
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