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The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway

Metabolism-mediated epigenetic changes represent an adapted mechanism for cellular signaling, in which lysine acetylation and methylation have been the historical focus of interest. We recently discovered a β-hydroxybutyrate–mediated epigenetic pathway that couples metabolism to gene expression. How...

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Vydáno v:Sci Adv
Hlavní autoři: Huang, He, Zhang, Di, Weng, Yejing, Delaney, Kyle, Tang, Zhanyun, Yan, Cong, Qi, Shankang, Peng, Chao, Cole, Philip A., Roeder, Robert G., Zhao, Yingming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904266/
https://ncbi.nlm.nih.gov/pubmed/33627428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe2771
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