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Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective
Recent work of Sottoriva, Graham, and collaborators have led to the controversial claim that exponentially growing tumors have a site frequency spectrum that follows the 1/f law consistent with neutral evolution. This conclusion has been criticized based on data quality issues, statistical considera...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904140/ https://ncbi.nlm.nih.gov/pubmed/33571199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008701 |
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