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Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective

Recent work of Sottoriva, Graham, and collaborators have led to the controversial claim that exponentially growing tumors have a site frequency spectrum that follows the 1/f law consistent with neutral evolution. This conclusion has been criticized based on data quality issues, statistical considera...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Tung, Hwai-Ray, Durrett, Rick
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904140/
https://ncbi.nlm.nih.gov/pubmed/33571199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008701
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