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POPULATION GENETICS OF NEUTRAL MUTATIONS IN EXPONENTIALLY GROWING CANCER CELL POPULATIONS
In order to analyze data from cancer genome sequencing projects, we need to be able to distinguish causative, or “driver,” mutations from “passenger” mutations that have no selective effect. Toward this end, we prove results concerning the frequency of neutural mutations in exponentially growing mul...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3588108/ https://ncbi.nlm.nih.gov/pubmed/23471293 |
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