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Importin α phosphorylation promotes TPX2 activation by GM130 to control astral microtubules and spindle orientation
Spindle orientation is important in multiple developmental processes as it determines cell fate and function. The orientation of the spindle depends on the assembly of a proper astral microtubule network. Here, we report that the spindle assembly factor TPX2 regulates astral microtubules. TPX2 in th...
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| Опубликовано в: : | J Cell Sci |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists Ltd
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904092/ https://ncbi.nlm.nih.gov/pubmed/33526712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.258356 |
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