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Importin α phosphorylation promotes TPX2 activation by GM130 to control astral microtubules and spindle orientation

Spindle orientation is important in multiple developmental processes as it determines cell fate and function. The orientation of the spindle depends on the assembly of a proper astral microtubule network. Here, we report that the spindle assembly factor TPX2 regulates astral microtubules. TPX2 in th...

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Detaylı Bibliyografya
Yayımlandı:J Cell Sci
Asıl Yazarlar: Guo, Haijing, Wei, Jen-Hsuan, Zhang, Yijun, Seemann, Joachim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7904092/
https://ncbi.nlm.nih.gov/pubmed/33526712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.258356
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