Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01

Parkinson’s disease is characterized by the loss of dopaminergic neurons in the substantia nigra leading to disabling deficits. Dopamine neuron grafts may provide a significant therapeutic advance over current therapies. We have generated midbrain dopamine neurons from human embryonic stem cells and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stem Cell
Prif Awduron: Piao, Jinghua, Zabierowski, Susan, Dubose, Brittany N., Hill, Ellen J., Navare, Monalisa, Claros, Nidia, Rosen, Siera, Ramnarine, Kiran, Horn, Callie, Fredrickson, Craig, Wong, Karen, Safford, Brent, Kriks, Sonja, El Maarouf, Abderrahman, Rutishauser, Urs, Henchcliffe, Claire, Wang, Yongzeng, Riviere, Isabelle, Mann, Shannon, Bermudez, Vladimir, Irion, Stefan, Studer, Lorenz, Tomishima, Mark, Tabar, Viviane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903922/
https://ncbi.nlm.nih.gov/pubmed/33545080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.01.004
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