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Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment

Embryonic stem cells (ESCs) represent a promising source of midbrain dopaminergic (DA) neurons for applications in Parkinson disease. However, ESC-based transplantation paradigms carry a risk of introducing inappropriate or tumorigenic cells. Cell purification before transplantation may alleviate th...

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Bibliografiske detaljer
Main Authors: Ganat, Yosif M., Calder, Elizabeth L., Kriks, Sonja, Nelander, Jenny, Tu, Edmund Y., Jia, Fan, Battista, Daniela, Harrison, Neil, Parmar, Malin, Tomishima, Mark J., Rutishauser, Urs, Studer, Lorenz
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408729/
https://ncbi.nlm.nih.gov/pubmed/22751106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58767
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