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Synthesis of an Hsp70 inhibitor and its assessment of lysosomal membrane permeabilization

Hsp70 inhibitors have great potential as chemical probes and anticancer agents. Thus, it is important to elucidate their modes of action on cancer cell death. This protocol describes a step-by-step process for the synthesis of apoptozole as an inhibitor of Hsp70, analysis of internalization of apopt...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: Park, Sang-Hyun, Park, Sookil, Shin, Injae
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903460/
https://ncbi.nlm.nih.gov/pubmed/33665629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100349
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