Application of a Highly Selective Cathepsin S Two-step Activity-Based Probe in Multicolor Bio-Orthogonal Correlative Light-Electron Microscopy

Cathepsin S is a lysosomal cysteine protease highly expressed in immune cells such as dendritic cells, B cells and macrophages. Its functions include extracellular matrix breakdown and cleavage of cell adhesion molecules to facilitate immune cell motility, as well as cleavage of the invariant chain...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Chem
Prif Awduron: van Dalen, Floris J., Bakkum, Thomas, van Leeuwen, Tyrza, Groenewold, Mirjam, Deu, Edgar, Koster, Abraham J., van Kasteren, Sander I., Verdoes, Martijn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903248/
https://ncbi.nlm.nih.gov/pubmed/33644004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.628433
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