Application of a Highly Selective Cathepsin S Two-step Activity-Based Probe in Multicolor Bio-Orthogonal Correlative Light-Electron Microscopy

Cathepsin S is a lysosomal cysteine protease highly expressed in immune cells such as dendritic cells, B cells and macrophages. Its functions include extracellular matrix breakdown and cleavage of cell adhesion molecules to facilitate immune cell motility, as well as cleavage of the invariant chain...

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Библиографические подробности
Опубликовано в: :Front Chem
Главные авторы: van Dalen, Floris J., Bakkum, Thomas, van Leeuwen, Tyrza, Groenewold, Mirjam, Deu, Edgar, Koster, Abraham J., van Kasteren, Sander I., Verdoes, Martijn
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903248/
https://ncbi.nlm.nih.gov/pubmed/33644004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.628433
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